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Anti-WDR26 antibody

产品货号 产品 品牌 单位 存货 价格 促销价 数量  
AB-06-4638
Anti-WDR26 antibody
洱畔/Erpan Tech 有货

产品特性        

Product type: Primary antibody
Antigen: WDR26
Immunogen: KLH conjugated synthetic peptide derived from human WDR26 101-200/514
Species immunized: Rabbit
Isotype: IgG
Applications: Western Blot(1:450-1:2000); Immunohistochemistry-Paraffin(1:450-1:800); Flow Cytometry (1)
Reactivity: Human, Mouse, Rat, Chicken, Dog, Cow, Horse
Clonality (clone number): Polyclonal
Form: Liquid
Buffer: Tris-HCl buffer (pH7.4), 1% BSA, 50% glycerol, 0.03% Proclin
Concentration: 1mg/ml
Purity: Protein A affinity purified.
Storage: Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles.
Alternative names: Myocardial ischemic preconditioning upregulated protein 2
WDR26
PRO0852
CDW2
MIP2
CUL4 and DDB1 associated WDR protein 2
Myocardial ischemic preconditioning up regulated protein 2
Myocardial ischemic preconditioning upregulated protein 2
WD repeat domain 26
WD repeat-containing protein 26
FLJ21016
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靶标信息

G-beta-like protein involved in cell signal transduction . Acts as a negative regulator in MAPK signaling pathway. Functions as a scaffolding protein to promote G beta:gamma-mediated PLCB2 plasma membrane translocation and subsequent activation in leukocytes . Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1 . Acts as a negative regulator of the canonical Wnt signaling pathway through preventing ubiquitination of beta-catenin CTNNB1 by the beta-catenin destruction complex, thus negatively regulating CTNNB1 degradation . Serves as a scaffold to coordinate PI3K/AKT pathway-driven cell growth and migration . Protects cells from oxidative stress-induced apoptosis via the down-regulation of AP-1 transcriptional activity as well as by inhibiting cytochrome c release from mitochondria . Protects also cells by promoting hypoxia-mediated autophagy and mitophagy (By similarity).

产品来源

洱泮科技实验室