Anti-VIMP antibody
产品特性
| Product type: | Primary antibody |
| Antigen: | Visfatin |
| Immunogen: | KLH conjugated synthetic peptide derived from human PBEF 301-400/491 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot(1:450-1:2000); Immunohistochemistry-Paraffin(1:400-1:850) |
| Reactivity: | Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Monkey |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 50% glycerol, 0.03% Proclin |
| Concentration: | 1mg/ml |
| Purity: | Peptide affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Pre-B-cell colony-enhancing factor 1 |
| PBEF1 protein | |
| AI480535 | |
| 1110035O14Rik | |
| AI314458 | |
| DKFZP666B131 | |
| EC 2.4.2.12 | |
| MGC117256 | |
| NAmPRTase | |
| NAMPT | |
| Nicotinamide phosphoribosyltransferase | |
| PBEF | |
| PBEF1 | |
| Pre B cell colony enhancing factor 1 | |
| Pre B cell colony enhancing factor | |
| Pre B cell enhancing factor | |
| Visfatin |
靶标信息
Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellular space and plasma. Plays a role in the modulation of circadian clock function. NAMPT-dependent oscillatory production of NAD regulates oscillation of clock target gene expression by releasing the core clock component: CLOCK-ARNTL/BMAL1 heterodimer from NAD-dependent SIRT1-mediated suppression (By similarity).
产品来源
洱泮科技实验室
