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Anti-VE Cadherin antibody
产品特性
| Product Cat#: | AB-06-4587 |
| Product type: | Primary antibody |
| Antigen: | VE Cadherin |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:900-1:5000); Immunoprecipitation |
| Reactivity: | Mouse |
| Clonality (clone number): | Monoclonal (JJ0941) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 50% glycerol, 0.03% Proclin |
| Concentration: | 1mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | 7B 4 antibody |
| 7B4 antibody | |
| 7B4 antigen antibody | |
| CADH5_HUMAN antibody | |
| Cadherin 5 antibody | |
| Cadherin 5 type 2 antibody | |
| Cadherin 5, type 2 (vascular endothelium) antibody | |
| Cadherin 5, type 2, VE cadherin (vascular epithelium) antibody | |
| Cadherin, vascular endothelial antibody | |
| Cadherin, vascular endothelial, 1 antibody | |
| Cadherin-5 antibody | |
| Cadherin5 antibody | |
| CD 144 antibody | |
| CD144 antibody | |
| CD144 antigen antibody | |
| CDH 5 antibody | |
| CDH5 antibody | |
| CDH5 protein antibody | |
| Endothelial specific cadherin antibody | |
| FLJ17376 antibody | |
| OTTHUMP00000174777 antibody | |
| Vascular endothelial cadherin antibody | |
| Vascular epithelium cadherin antibody | |
| VE Cad antibody | |
| VE-cadherin antibody | |
| VEC antibody |
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靶标信息
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. Inhibits the pro-apoptotic function of KREMEN1 in a Wnt-independent manner, and has anti-apoptotic activity (By similarity).
产品来源
洱畔科技实验室