Anti-TIMP-1 antibody
产品特性
| Product Cat#: | AB-06-4360 |
| Product type: | Primary antibody |
| Antigen: | TIMP-1 |
| Immunogen: | Recombinant protein |
| Species immunized: | Mouse |
| Isotype: | IgG |
| Applications: | Western Blot (1:400-1:2000); Immunohistochemistry-Paraffin (1:500-1:800); Immunofluorescence (1:200-1:850); Immunocytochemistry (1:80-1:200) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Monoclonal (4C2) |
| Form: | Liquid |
| Buffer: | 10 mM Tris-HCl buffer (pH 7.4), 1% BSA, 50% glycerol, 0.03% Proclin. |
| Concentration: | 1 mg/ml |
| Purity: | Protein G affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Clgi |
| Collagenase inhibitor | |
| EPA | |
| EPO | |
| Erythroid Potentiating Activity | |
| Fibroblast collagenase inhibitor | |
| FLJ90373 | |
| HC | |
| Human Collagenase Inhibitor | |
| Metalloproteinase inhibitor 1 | |
| Metalloproteinase inhibitor 1 precursor | |
| OTTHUMP00000023214 | |
| TIMP 1 | |
| TIMP | |
| TIMP metallopeptidase inhibitor 1 | |
| TIMP1 protein | |
| Tissue Inhibitor of Metalloproteinase 1 | |
| Tissue inhibitor of metalloproteinases |
展开
靶标信息
Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. Mediates erythropoiesis in vitro; but, unlike IL3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors.
产品来源
洱畔科技实验室
