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Anti-Fragilis antibody

产品货号 产品 品牌 单位 存货 价格 促销价 数量  
AB-06-1771
Anti-Fragilis antibody
洱畔/Erpan Tech 有货

产品特性        

Product type: Primary antibody
Antigen: Fragilis
Immunogen: Recombinant protein
Species immunized: Rabbit
Isotype: IgG
Applications: Western Blot (1:900-1:5000); Immunohistochemistry (1:40-1:100); Flow Cytometry (1:40-1:100); Immunocytochemistry (1:40-1:200)
Reactivity: Human
Clonality (clone number): Monoclonal (JU73-02)
Form: Liquid
Buffer: Tris-HCl buffer (pH7.4), 1% BSA, 40% glycerol, 0.05% NaN3.
Concentration: 1mg/ml
Purity: Protein A affinity purified
Storage: Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles.
Alternative names: 1 8U antibody
Fragilis antibody
IFITM3 antibody
IFM3_HUMAN antibody
Interferon induced transmembrane protein 3 (1 8U) antibody
Interferon Induced Transmembrane Protein 3 antibody
Interferon inducible antibody
Interferon inducible protein 1 8U antibody
Interferon Inducible Protein 15 antibody
Interferon Inducible Protein Homolog antibody
Interferon-induced transmembrane protein 3 antibody
Interferon-inducible protein 1-8U antibody
IP15 antibody
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靶标信息

IFN-induced antiviral protein which disrupts intracellular cholesterol homeostasis. Inhibits the entry of viruses to the host cell cytoplasm by preventing viral fusion with cholesterol depleted endosomes. May inactivate new enveloped viruses which buds out of the infected cell, by letting them go out with a cholesterol depleted membrane. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV) and Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and vesicular stomatitis virus (VSV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry, SARS-CoV S protein-mediated viral entry and VSV G protein-mediated viral entry. Plays a critical role in the structural stability and function of vacuolar ATPase (v-ATPase). Establishes physical contact with the v-ATPase of endosomes which is critical for proper clathrin localization and is also required for the function of the v-ATPase to lower the pH in phagocytic endosomes thus establishing an antiviral state.

产品来源

洱畔科技实验室

文件下载

Material-Safety-Data-Sheet.pdf (下载56157 )