Anti-MyD88 antibody
产品特性
| Product Cat#: | AB-06-3017 |
| Product type: | Primary antibody |
| Antigen: | MyD88 |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:1000); Immunohistochemistry (1:50-1:200); Flow Cytometry (1:50-1:100); Immunocytochemistry (1:100-1:500); Immunofluorescence |
| Clonality (clone number): | Monoclonal (SC65-04) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% Glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles |
| Alternative names: | Mutant myeloid differentiation primary response 88 antibody |
| MYD 88 antibody | |
| Myd88 antibody | |
| MYD88_HUMAN antibody | |
| MYD88D antibody | |
| Myeloid differentiation marker 88 antibody | |
| Myeloid differentiation primary response 88 antibody | |
| Myeloid differentiation primary response gene (88) antibody | |
| Myeloid differentiation primary response gene 88 antibody | |
| Myeloid differentiation primary response gene antibody | |
| Myeloid differentiation primary response protein MyD88 antibody | |
| OTTHUMP00000161718 antibody | |
| OTTHUMP00000208595 antibody | |
| OTTHUMP00000209058 antibody | |
| OTTHUMP00000209059 antibody | |
| OTTHUMP00000209060 antibody |
靶标信息
Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response (PubMed:15361868, PubMed:18292575). Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (PubMed:15361868, PubMed:24316379, PubMed:19506249). Increases IL-8 transcription (PubMed:9013863). Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes. MyD88-mediated signaling in intestinal epithelial cells is crucial for maintenance of gut homeostasis and controls the expression of the antimicrobial lectin REG3G in the small intestine (By similarity).
产品来源
洱畔科技实验室