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Anti-FOXP3 antibody

产品货号 产品 品牌 单位 存货 价格 促销价 数量  
AB-06-1764
Anti-FOXP3 antibody
洱畔/Erpan Tech 有货

产品特性        

Product type: Primary antibody
Antigen: FOXP3
Immunogen: Recombinant protein
Species immunized: Rabbit
Isotype: IgG
Applications: Flow Cytometry (1:40-1:100); Immunocytochemistry (1:20-1:200)
Reactivity: Human
Clonality (clone number): Monoclonal (JF0898)
Form: Liquid
Buffer: Tris-HCl buffer (pH7.4), 1% BSA, 40% glycerol, 0.05% NaN3.
Concentration: 1mg/ml
Purity: Protein A affinity purified
Storage: Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles.
Alternative names: AIID antibody
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靶标信息

Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. Inhibits the pro-apoptotic function of KREMEN1 in a Wnt-independent manner, and has anti-apoptotic activity (By similarity).

产品来源

洱畔科技实验室

文件下载

Material-Safety-Data-Sheet.pdf (下载47239)