Anti-Tetranectin antibody
产品特性
| Product Cat#: | AB-06-4309 |
| Product type: | Primary antibody |
| Antigen: | Tetranectin |
| Immunogen: | Recombinant protein within human Tetranectin aa 100-250. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:800-1:5000); Immunohistochemistry (1:100-1:200); Immunocytochemistry (1:100-1:200); Immunoprecipitation(1:20-1:50) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Monoclonal (JG37-16) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | C type lectin domain family 3 member B antibody |
| C-type lectin domain family 3 member B antibody | |
| Clec3b antibody | |
| Plasminogen kringle 4 binding protein antibody | |
| Plasminogen kringle 4-binding protein antibody | |
| TETN_HUMAN antibody | |
| Tetranectin (plasminogen binding protein) antibody | |
| Tetranectin antibody | |
| TN antibody |
靶标信息
Tetranectin is a homotrimeric glycoprotein present in plasma and various tissue locations that binds to calcium, heparin, and plasminogen kringle 4. Tetranectin may play a prominent role in tissue remodeling as well as in the regulation of proteolytic processes via its binding and indirect activation of plasminogen. Tetranectin is found in the extracellular matrix (ECM) of certain carcinomas, but is not present in the ECM of normal tissues. Extracellular proteolysis is an important factor in the ability of malignant cells to penetrate normal tissues and metastasize. Decreased plasma tetranectin or increased tetranectin in stroma of cancers correlates with cancer progression and a grim prognosis. Tetranectin may also influence cancer growth by altering activities of plasminogen or the plasminogen fragment, angiostatin which inhibits tumor cell proliferation.
产品来源
洱畔科技实验室
