Anti-HIF-1 beta antibody
产品特性
| Product Cat#: | AB-06-2159 |
| Product type: | Primary antibody |
| Antigen: | HIF-1 beta |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:800-1:2000); Immunohistochemistry (1:100-1:200) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal (ST05-25) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | arnT antibody |
| ARNT protein antibody | |
| ARNT_HUMAN antibody | |
| Aryl hydrocarbon receptor nuclear translocator antibody | |
| BHLHe2 antibody | |
| Class E basic helix-loop-helix protein 2 antibody | |
| Dioxin receptor antibody | |
| Dioxin receptor nuclear translocator antibody | |
| Drnt antibody | |
| HIF 1 beta antibody | |
| HIF 1beta antibody | |
| HIF-1-beta antibody | |
| HIF1-beta antibody | |
| HIF1B antibody | |
| HIF1beta antibody | |
| Hypoxia Inducible Factor 1 antibody | |
| Hypoxia inducible factor 1 beta antibody | |
| Hypoxia-inducible factor 1-beta antibody | |
| nuclear translocator antibody | |
| Tango antibody |
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靶标信息
Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer binds to core DNA sequence 5′-TACGTG-3′ within the hypoxia response element (HRE) of target gene promoters and functions as a transcriptional regulator of the adaptive response to hypoxia (By similarity). The heterodimer ARNT:AHR binds to core DNA sequence 5′-TGCGTG-3′ within the dioxin response element (DRE) of target gene promoters and activates their transcription (PubMed:28396409).
产品来源
洱畔科技实验室