Anti-FLVCR antibody
产品特性
| Product Cat#: | AB-06-1740 |
| Product type: | Primary antibody |
| Antigen: | FLVCR |
| Immunogen: | KLH conjugated synthetic peptide derived from Human FLVCR 451-550/555 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:400-1:2000); Immunohistochemistry-Paraffin (1:500-800) |
| Reactivity: | Human, Mouse, Rat, Chicken, Pig, Horse |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 0.01 M TBS(pH7.4) with 1% BSA; 0.03% Proclin 300 and 50% Glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Feline leukemia virus subgroup C cellular receptor |
| Feline leukemia virus subgroup C receptor | |
| Feline leukemia virus subgroup C receptor related protein 1 | |
| Feline leukemia virus subgroup C receptor-related protein 1 | |
| FLVC1_HUMAN | |
| FLVCR1 | |
| FLVCR protein | |
| FLVCR1 |
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靶标信息
Isoform 1: Heme transporter that exports cytoplasmic heme. It can also export coproporphyrin and protoporphyrin IX, which are both intermediate products in the heme biosynthetic pathway. Does not export bilirubin. Heme export depends on the presence of HPX and is required to maintain intracellular free heme balance, protecting cells from heme toxicity. Heme export provides protection from heme or ferrous iron toxicities in liver, brain, sensory neurons and during erythtopoiesis, a process in which heme synthesis intensifies. Causes susceptibility to FeLV-C in vitro.
Isoform 2: Heme transporter that promotes heme efflux from the mitochondrion to the cytoplasm. Essential for erythroid differentiation.
产品来源
洱畔科技实验室
