Anti-RALB antibody
产品特性
| Product Cat#: | AB-06-3814 |
| Product type: | Primary antibody |
| Antigen: | RALB |
| Immunogen: | Recombinant protein |
| Species immunized: | Mouse |
| Isotype: | IgG2b |
| Applications: | Western Blot (1:500-1:2000); Immunohistochemistry (1:50-1:200); Flow Cytometry (1:50-1:200) |
| Reactivity: | Human, Mouse, Monkey |
| Clonality (clone number): | Monoclonal (B4-F8) |
| Form: | Liquid |
| Buffer: | TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Alternative names: | 5730472O18Rik antibody |
| dRalb antibody | |
| GTP binding protein antibody | |
| Ralb antibody | |
| RALB_HUMAN antibody | |
| RAS like protein B antibody | |
| Ras related GTP binding protein B antibody | |
| Ras-related protein Ral-B antibody | |
| v ral simian leukemia viral oncogene homolog B (ras related GTP binding protein) antibody | |
| v ral simian leukemia viral oncogene homolog B (ras related) |
靶标信息
Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. The RALA-exocyst complex regulates integrin-dependent membrane raft exocytosis and growth signaling (PubMed:20005108). Key regulator of LPAR1 signaling and competes with GRK2 for binding to LPAR1 thus affecting the signaling properties of the receptor. Required for anchorage-independent proliferation of transformed cells (PubMed:19306925). During mitosis, supports the stabilization and elongation of the intracellular bridge between dividing cells. Cooperates with EXOC2 to recruit other components of the exocyst to the early midbody (PubMed:18756269).
产品来源
洱畔科技实验室
