Anti-IL-4R Antibody
产品特性
| Product Cat#: | AB-06-2423 |
| Product type: | Primary antibody |
| Antigen: | IL-4R |
| Immunogen: | KLH conjugated synthetic peptide derived from human IL-4R 201-300/825 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:800-1:2000); Immunocytochemistry (1:80-1:500); Immunofluorescence; Flow Cytometry (1-2μg /test) |
| Reactivity: | Mouse, Rat, Pig, Horse and Human |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Interleukin-4 Receptor |
| 582J2.1 | |
| CD124 | |
| CD-124 | |
| CD 124 | |
| IL 4R alpha | |
| IL4RA | |
| Interleukin 4 receptor alpha chain | |
| MGC118473 |
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靶标信息
Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2.Soluble IL4R (sIL4R) inhibits IL4-mediated cell proliferation and IL5 up-regulation by T-cells.
产品来源
洱畔科技实验室
