Anti-KIAA1598 antibody
产品特性
| Product Cat#: | AB-06-2592 |
| Product type: | Primary antibody |
| Antigen: | KIAA1598 |
| Immunogen: | KLH conjugated synthetic peptide derived from human KIAA1598 21-130/631 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Immunohistochemistry-Paraffin (1:400-1:800); Western Blot |
| Reactivity: | Human, Mouse, Rat, Pig, Cow, Horse |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 10 mM TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Alternative names: | DKFZp686A0439 |
| Hypothetical Protein FLJ11122 | |
| Kiaa1598 | |
| MGC40476 | |
| Putative Uncharacterized Protein KIAA1598 | |
| Shootin 1 | |
| Shootin-1 | |
| Shootin | |
| SHOT1_HUMAN |
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靶标信息
Involved in the generation of internal asymmetric signals required for neuronal polarization and neurite outgrowth. Mediates netrin-1-induced F-actin-substrate coupling or ‘clutch engagement’ within the axon growth cone through activation of CDC42, RAC1 and PAK1-dependent signaling pathway, thereby converting the F-actin retrograde flow into traction forces, concomitantly with filopodium extension and axon outgrowth.
产品来源
洱畔科技实验室
