Anti-3mC antibody Recombinant Rabbit monoclonal Antibody
产品特性
| Product Cat#: | AB-06-6000 |
| Product type: | Primary antibody |
| Antigen: | 3mC |
| Immunogen: | 3-mc-OVA |
| Molecular weight: | Predicted band size: – kDa |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Immunocytochemistry/Immunofluorescence (1:500-1:100); Dot Blot (1:2000) |
| Reactivity: | Species independent |
| Clonality (clone number): | Monoclonal, PSH03-21 |
| Form: | Liquid |
| Buffer: | 1*PBS buffer (pH7.4), 40% glycerol, 0.05% BSA, 0.05% NaN3. |
| Concentration: | 1 mg/mL |
| Purity: | Protein A affinity purified. |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: |
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靶标信息
Methylation of DNA can occur non-enzymatically at the nitrogen-three of the cytosine base through spontaneous exposure to endogenous S-adenosyl methionine (SAM). The resulting 3-methylcytosine (3-mC) is mutagenic and must be repaired, which occurs in humans through the base excision repair (BER) or dealkylation via human homologues of the E. coli AlkB protein. 3-methylcytosine is present in human cell lines and increased levels of 3-mC impair proliferation.
产品来源
洱畔科技实验室
