重组Anti-Syndecan-1抗体[EPR6454] (ab128936)
产品特性
| Product Cat#: | ab128936 |
| Product type: | Primary antibody |
| Antigen: | Syndecan-1 |
| Immunogen: | Recombinant fragment. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Flow Cyt (Intra), ICC/IF, WB, IHC-P |
| Reactivity: | Mouse, Rat and Human |
| Clonality (clone number): | Monoclonal, EPR6454 |
| Form: | Liquid |
| Buffer: | pH: 7.2 |
| Preservative: 0.01% Sodium azide | |
| Constituents: 59% PBS, 40% Glycerol, 0.05% BSA | |
| Concentration: | 0.996 mg/ml |
| Purity: | Protein A purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | CD_antigen antibody |
| CD138 antibody | |
| CD138 antigen antibody | |
| heparan sulfate proteoglycan fibroblast growth factor receptor antibody | |
| SDC antibody | |
| Sdc1 antibody | |
| SDC1_HUMAN antibody | |
| SYND1 antibody | |
| Syndecan 1 antibody | |
| Syndecan antibody | |
| syndecan proteoglycan 1 antibody | |
| Syndecan-1 antibody |
靶标信息
Cell surface proteoglycan that contains both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix (By similarity).
Regulates exosome biogenesis in concert with SDCBP and PDCD6IP (PubMed:22660413).
Able to induce its own expression in dental mesenchymal cells and also in the neighboring dental epithelial cells via an MSX1-mediated pathway (By similarity).
相关文献
1、Mo YQ, Nakamura H, Tanaka T, Odani T, Perez P, Ji Y, French BN, Pranzatelli TJ, Michael DG, Yin H, Chow SS, Khalaj M, Afione SA, Zheng C, Oliveira FR, Motta ACF, Ribeiro-Silva A, Rocha EM, Nguyen CQ, Noguchi M, Atsumi T, Warner BM, Chiorini JA. Lysosomal exocytosis of HSP70 stimulates monocytic BMP6 expression in Sjögren’s syndrome. J Clin Invest. 2022 Mar 15;132(6):e152780. doi: 10.1172/JCI152780. PMID: 35113815; PMCID: PMC8920330.
2、Zou Z, Li L, Li Q, Zhao P, Zhang K, Liu C, Cai D, Maegele M, Gu Z, Huang Q. The role of S100B/RAGE-enhanced ADAM17 activation in endothelial glycocalyx shedding after traumatic brain injury. J Neuroinflammation. 2022 Feb 11;19(1):46. doi: 10.1186/s12974-022-02412-2. PMID: 35148784; PMCID: PMC8832692.
3、Zhang Y, Chen Y, Zhang Z, Tao X, Xu S, Zhang X, Zurashvili T, Lu Z, Bayascas JR, Jin L, Zhao J, Zhou X. Acox2 is a regulator of lysine crotonylation that mediates hepatic metabolic homeostasis in mice. Cell Death Dis. 2022 Mar 29;13(3):279. doi: 10.1038/s41419-022-04725-9. PMID: 35351852; PMCID: PMC8964741.
