购物车里没有产品

五星推荐产品

重组Anti-C3抗体[EPR19394] (ab200999)

产品货号 产品 品牌 单位 存货 价格 促销价 数量  
ab200999
重组Anti-C3抗体[EPR19394] (ab200999)
abcam 40 μL;100 μL;1 mL 有货
询价

产品特性        

Product Cat#: ab200999
Product type: Primary antibody
Antigen: C3
Immunogen: Synthetic peptide.
Species immunized: Rabbit
Isotype: IgG
Applications: WB,  IHC-P
Reactivity: Mouse, Rat and Human
Clonality (clone number): Monoclonal, EPR19394
Form: Liquid
Buffer: pH: 7.2
Preservative: 0.01% Sodium azide
Constituents: 59% PBS, 40% Glycerol, 0.05% BSA
Concentration: 批次浓度范围 100 µl 浓度为 0.864 – 0.912 mg/ml
1 ml 浓度为 0.791 mg/ml
40 µl 浓度为 0.864 mg/ml
Purity: Protein A purified
Storage: Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles.
Alternative names: Acylation stimulating protein cleavage product antibody
AHUS5 antibody
ARMD9 antibody
ASP antibody
C3 and PZP like alpha 2 macroglobulin domain containing protein 1 antibody
C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1 antibody
C3 antibody
c3 complement antibody
C3adesArg antibody
CO3_HUMAN antibody
Complement C3 alpha chain antibody
Complement C3 antibody
Complement C3b alpha' chain antibody
Complement C3c alpha' chain fragment 1 antibody
Complement C3c alpha' chain fragment 2 antibody
Complement C3c alpha" chain fragment 2 antibody
Complement C3d fragment antibody
Complement C3dg fragment antibody
Complement C3f fragment antibody
Complement C3g fragment antibody
Complement component 3 antibody
Complement factor 3 antibody
CPAMD1 antibody
HEL S 62p antibody
omplement C3 beta chain antibody
展开

靶标信息

C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates.
Derived from proteolytic degradation of complement C3, C3a anaphylatoxin is a mediator of local inflammatory process. In chronic inflammation, acts as a chemoattractant for neutrophils (By similarity).
It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes

相关文献

1、Xie T  et al. Insight into the Neuroprotective Effect of Genistein-3′-Sodium Sulfonate Against Neonatal Hypoxic-Ischaemic Brain Injury in Rats by Bioinformatics. Mol Neurobiol 60:807-819 (2023).

2、Choi YJ  et al. Promotion of the inflammatory response in mid colon of complement component 3 knockout mice. Sci Rep 12:1700 (2022).

3、Meng S  et al. Age of Rats Affects the Degree of Retinal Neuroinflammatory Response Induced by High Acute Intraocular Pressure. Dis Markers 2022:9404977 (2022).