重组Anti-GSDMD抗体[EPR19828] (ab209845)
产品特性
| Product Cat#: | ab209845 |
| Product type: | Primary antibody |
| Antigen: | GSDMD |
| Immunogen: | Synthetic peptide. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | WB, IP |
| Reactivity: | Mouse |
| Clonality (clone number): | Monoclonal, EPR19828 |
| Form: | Liquid |
| Buffer: | pH: 7.2 |
| Preservative: 0.01% Sodium azide | |
| Constituents: 59% PBS, 40% Glycerol, 0.05% BSA | |
| Concentration: | - mg/mL |
| Purity: | Protein A purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | DF5L |
| DFNA5L | |
| FKSG10 | |
| FLJ12150 | |
| gasdermin D | |
| gasdermin domain containing 1 | |
| Gasdermin domain-containing protein 1 | |
| gasdermin-D | |
| GSDMD N | |
| GSDMD | |
| GSDMDC1 | |
| GSDMD-N | |
| hGSDMD-CTD |
靶标信息
Gasdermin D is a member of the gasdermin family. Members of this family appear to play a role in regulation ofepithelial proliferation. Gasdermin D has been suggested to act as a tumor suppressor. Alternatively splicedtranscript variants have been described. (provided by RefSeq)
相关文献
1、Li Y et al. Bacterial outer membrane vesicles-based therapeutic platform eradicates triple-negative breast tumor by combinational photodynamic/chemo-/immunotherapy. Bioact Mater 20:548-560 (2023).
2、Zhang LM et al. STING mediates neuroinflammatory response by activating NLRP3-related pyroptosis in severe traumatic brain injury. J Neurochem 162:444-462 (2022).
3、Feng S et al. Pathogen-selective killing by guanylate-binding proteins as a molecular mechanism leading to inflammasome signaling. Nat Commun 13:4395 (2022).
4、Li X et al. Caspase-1 and Gasdermin D Afford the Optimal Targets with Distinct Switching Strategies in NLRP1b Inflammasome-Induced Cell Death. Research (Wash D C) 2022:9838341 (2022).
