Anti-DAAM1 Rabbit Polyclonal antibody
产品特性
| Product Cat#: | AB-06-5075 |
| Product type: | Primary antibody |
| Antigen: | DAAM1 |
| Immunogen: | Synthetic peptide from human protein at AA 400-500. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2000) |
| Reactivity: | Human, Mouse |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 1*PBS buffer (pH 7.4), 0.5% BSA, 50% glycerol, 0.02% NaN3. |
| Concentration: | 1 mg/mL |
| Purity: | Immunogen affinity purified. |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Disheveled-associated activator of morphogenesis 1 antibody; DAAM1 |
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靶标信息
Binds to disheveled (Dvl) and Rho, and mediates Wnt-induced Dvl-Rho complex formation. May play a role as a scaffolding protein to recruit Rho-GDP and Rho-GEF, thereby enhancing Rho-GTP formation. Can direct nucleation and elongation of new actin filaments. Involved in building functional cilia (PubMed:16630611, PubMed:17482208).
Involved in the organization of the subapical actin network in multiciliated epithelial cells (By similarity).
Together with DAAM2, required for myocardial maturation and sarcomere assembly (By similarity).
产品来源
洱畔科技实验室
