Anti-CASC5 antibody
产品特性
| Product type: | Primary antibody |
| Antigen: | CASC5 |
| Immunogen: | KLH conjugated synthetic peptide derived from human CASC5 2251-2342/2342 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:400-1:2000) |
| Reactivity: | Human, Mouse, Rat, Dog, Cow, Horse, Rabbit |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Concentration: | 1mg/ml |
| Purity: | Protein A/G affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Protein D40/AF15q14 |
| AF15Q14 | |
| ALL1 fused gene from chromosome 15q14 | |
| Blinkin bub linking kinetochore protein | |
| Cancer susceptibility candidate 5 | |
| Cancer susceptibility candidate gene 5 protein | |
| Cancer/testis antigen 29 | |
| CT29 | |
| D40 | |
| HKNL 1 | |
| Hspc105 | |
| KIAA1570 | |
| Kinetochore null 1 homolog | |
| Kinetochore null protein 1 | |
| KNL1 |
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靶标信息
Performs two crucial functions during mitosis: it is essential for spindle-assembly checkpoint signaling and for correct chromosome alignment. Required for attachment of the kinetochores to the spindle microtubules. Directly links BUB1 and BUB1B to kinetochores. Part of the MIS12 complex, which may be fundamental for kinetochore formation and proper chromosome segregation during mitosis. Acts in coordination with CENPK to recruit the NDC80 complex to the outer kinetochore.
产品来源
洱畔科技实验室
