Anti-Smad1 (Ab-465) antibody
产品特性
| Product Cat#: | AB-07-3756 |
| Product type: | Primary antibody |
| Antigen: | Smad1 (Ab-465) |
| Immunogen: | A synthetic peptide derived from human Smad1 around the phosphorylation site of serine 465 (I-S-S-V-SP). The exact amino-acid sequence is proprietary. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500~1:3000); ELISA (1:5000); Immunohistochemistry (1:50~1:100) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | PBS (without Mg2+ and Ca2+ ), pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol |
| Concentration: | 1 mg/ml |
| Purity: | Antigen affinity chromatography |
| Storage: | Aliquot and freeze at -20°C. Avoid multiple freeze/thaw cycles. |
| Alternative names: | BSP-1; BSP1; Dwarfin-A; Dwf-A; JV4-1; Mad-related protein 1; Mad1; MADH1; MADR1; Mothers against decapentaplegic homolog 1; Mothers against DPP homolog 1; Mothers-against-DPP-related-1; Smad 1; SMAD 1; Transforming growth factor- beta signaling protein-1 |
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靶标信息
Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression.
产品来源
洱畔科技实验室
