Anti-Nuclear Receptor NR4A1 (Ab-351) antibody
产品特性
| Product Cat#: | AB-07-3380 |
| Product type: | Primary antibody |
| Antigen: | Nuclear Receptor NR4A1 |
| Immunogen: | A synthetic peptide derived from human Nuclear Receptor NR4A1 around the phosphorylation site of serine 351 (L-P-S/P-K-P). The exact amino-acid sequence is proprietary. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | ELISA (1:10000); Western Blot (1:500-1:2500); Immunohistochemistry (1:50-1:100) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | PBS (without Mg2+ and Ca2+ ), pH 7.4, 0.02% sodium azide and 50% glycerol |
| Concentration: | 1 mg/ml |
| Purity: | Antigen affinity chromatography |
| Storage: | Aliquot and freeze at -20°C. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Early response protein NAK1, GFRP, GFRP1, HMR, N10, N10 nuclear protein, NAK1, NGFI-B, NGFIB, NR4A1, Nuclear hormone receptor NUR/77, Orphan nuclear receptor HMR, TR3 orphan receptor |
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靶标信息
Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5′-AAAAGGTCA-3′ (By similarity). May inhibit NF-kappa-B transactivation of IL2. Participates in energy homeostasis by sequestrating the kinase STK11 in the nucleus, thereby attenuating cytoplasmic AMPK activation. Plays a role in the vascular response to injury (By similarity).
产品来源
洱畔科技实验室
