Rat Electrogenic Sodium Bicarbonate Cotransporter 1 (SLC4A4) ELISA kit
Specifications
| Product Cat#: | EK-07-0510 |
| Product name: | Rat Electrogenic Sodium Bicarbonate Cotransporter 1 (SLC4A4) ELISA kit |
| Target Name: | SLC4A4 |
| Species Reactivity: | Rat |
| Product Size: | 48/96 Tests |
| Sensitivity: | 0.08 ng/ml |
| Assay range: | 1.0-25 ng/ml |
| Assay Time: | 90 minutes |
| Platform: | Colorimetric Microplate Reader |
| Conjugate: | HRP |
| ELISA Type: | 25 ng/ml 反向 |
| Detection Method: | Colorimetric |
| Storage temperature: | Store at 2-8°C |
| Stability: | Stable within the expiration date under suggested storage conditions |
| Shipping condition: | Wet ice |
| Kit Contents: | Microtiter plate (1x), Enzyme conjugate (1 vial), Standard samples (6 vials), |
| Substrates (A & B, 2 vials), Stop solution (1 vial), Wash Solution (100x, 1 vial), | |
| Balance solution (1 vial), Instruction (1 copy) | |
| Other Names of Target: | DKFZp781H1314; Electrogenic Sodium Bicarbonate Cotransporter 1; hhNMC; HNBC 1; HNBC1; kNBC 1; KNBC; kNBC1; Na(+)/HCO3(-) Cotransporter; Na+HCO3- Cotransporter 4; NBC 1; NBC 2; NBC1; NBC2; Nbc4; NBCE 1; NBCE1; PNBC; SLC4A5; Sodium bicarbonate cotransporter Kidney; Sodium Bicarbonate Cotransporter Member 4; Sodium Bicarbonate Cotransporter Pancreas; Solute Carrier Family 4 Member 4; Solute Carrier Family 4 Sodium Bicarbonate Cotransporter Member 4; Solute Carrier Family 4 Sodium Bicarbonate Cotransporter Member 5; S4A4_HUMAN |
Target information
SLC4A4 (Electrogenic sodium bicarbonate cotransporter 1) is an electrogenic sodium/bicarbonate cotransporter with a Na(+):HCO3(-) stoichiometry varying from 1:2 to 1:3. It may regulate bicarbonate influx/efflux at the basolateral membrane of cells and regulate intracellular pH. SLC4A4 interacts with carbonic anhydrase 2 and carbonic anhydrase 4 which may regulate transporter activity. There are four named isoforms produced by alternative splicing.
This gene encodes a sodium bicarbonate cotransporter (NBC) involved in the regulation of bicarbonate secretion and absorption and intracellular pH. Mutations in this gene are associated with proximal renal tubular acidosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008].
Provider
Erpantech Laboratory
