Purified Rat Anti-Mouse GPIbα (CD42b) Monoclonal Antibody
Specifications
| Product Cat#: | M041-0 |
| Product type: | Primary antibody |
| Antigen: | GPIbα (CD42b) |
| Immunogen: | Recombinant protein |
| Species immunized: | Rat |
| Isotype: | IgG2a |
| Applications: | Immunohistochemistry; Flow Cytometry |
| Reactivity: | Mouse |
| Clonality (clone number): | Monoclonal, Xia.H10 |
| Form: | Liquid |
| Buffer: | 0.5 mg purified immunoglobulin in PBS and 0.09% (w/v) sodium azide |
| Concentration: | 0.5 mg/mL |
| Purity: | Protein G affinity purified. |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Platelet glycoprotein Ib alpha chain; GP-Ib alpha; GPIb-alpha; GPIbA; Glycoprotein Ibalpha; Gp1ba |
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Target information
The Xia.G5 antibody reacts with mouse GPIbalpha (CD42b), a platelet/megakaryocyte-specific polypeptide that is part of the GPIb-V-IX complex. The antibody binds to the N-terminal 45 kDa domain of GPIb alpha, which contains the binding sites for different ligands of the receptor, including vWf, thrombin, and P-selectin. GPIb alpha is proteolytically cleaved (glycocalicin) during platelet activation.
Provider
Erpantech Laboratory
