Mouse Perforin 1 ELISA kit
Specifications
| Product Cat#: | EK-07-1125 |
| Product name: | Mouse Perforin 1 ELISA kit |
| Target Name: | PRF1 |
| Species Reactivity: | Mouse |
| Product Size: | 48/96 Tests |
| Sensitivity: | 0.05 ng/ml |
| Assay range: | 0.5-10 ng/ml |
| Assay Time: | 90 minutes |
| Platform: | Colorimetric Microplate Reader |
| Conjugate: | HRP |
| ELISA Type: | Competitive ELISA |
| Detection Method: | Colorimetric |
| Storage temperature: | Store at 2-8°C |
| Stability: | Stable within the expiration date under suggested storage conditions |
| Shipping condition: | Wet ice |
| Kit Contents: | Microtiter plate (1x), Enzyme conjugate (1 vial), Standard samples (6 vials), |
| Substrates (A & B, 2 vials), Stop solution (1 vial), Wash Solution (100x, 1 vial), | |
| Balance solution (1 vial), Instruction (1 copy) | |
| Other Names of Target: | FLH2; HPLH2; P1; PFP; Pore forming protein; Cytolysin; Lymphocyte pore-forming protein |
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Target information
The protein encoded by this gene has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood. Alternative splicing results in multiple transcript variants encoding the same protein.
Provider
Erpantech Laboratory
