Mouse D Dimer ELISA kit
Specifications
| Product Cat#: | EK-07-0770 |
| Product name: | Mouse D Dimer ELISA kit |
| Target Name: | D2D |
| Species Reactivity: | Mouse |
| Product Size: | 48/96 Tests |
| Sensitivity: | 14.1 pg/ml |
| Assay range: | 100-2500 pg/ml |
| Assay Time: | 90 minutes |
| Platform: | Colorimetric Microplate Reader |
| Conjugate: | HRP |
| ELISA Type: | Competitive ELISA |
| Detection Method: | Colorimetric |
| Storage temperature: | Store at 2-8°C |
| Stability: | Stable within the expiration date under suggested storage conditions |
| Shipping condition: | Wet ice |
| Kit Contents: | Microtiter plate (1x), Enzyme conjugate (1 vial), Standard samples (6 vials), |
| Substrates (A & B, 2 vials), Stop solution (1 vial), Wash Solution (100x, 1 vial), | |
| Balance solution (1 vial), Instruction (1 copy) | |
| Other Names of Target: | D 2 Dimer |
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Target information
Participates in the repair of UV-damaged DNA by excising pyrimidine dimers that are the major UV-lesions. DNA glycosylase activity hydrolyzes the glycosylic bond of the 5′ pyrimidine of the dimer. This leaves apurinic/apyrimidic (AP) sites in the DNA. These AP sites are removed by the AP lyase activity which cleaves the intrapyrimidine phosphodiester bond. Catalysis proceeds via a protonated imine covalent intermediate between the alpha-amino group of the N-terminal threonine residue and the C1′ of the deoxyribose sugar of the 5′ pyrimidine at the dimer site.
References
Erpantech Laboratory
