Mouse ATP Binding Cassette Sub Family D Member 1 ELISA kit
Specifications
| Product Cat#: | EK-07-0967 |
| Product name: | Mouse ATP Binding Cassette Sub Family D Member 1 ELISA kit |
| Target Name: | ABCD 1 |
| Species Reactivity: | Mouse |
| Product Size: | 48/96 Tests |
| Sensitivity: | 11.1 pg/ml |
| Assay range: | 100-2500 pg/ml |
| Assay Time: | 90 minutes |
| Platform: | Colorimetric Microplate Reader |
| Conjugate: | HRP |
| ELISA Type: | Competitive ELISA |
| Detection Method: | Colorimetric |
| Storage temperature: | Store at 2-8°C |
| Stability: | Stable within the expiration date under suggested storage conditions |
| Shipping condition: | Wet ice |
| Kit Contents: | Microtiter plate (1x), Enzyme conjugate (1 vial), Standard samples (6 vials), |
| Substrates (A & B, 2 vials), Stop solution (1 vial), Wash Solution (100x, 1 vial), | |
| Balance solution (1 vial), Instruction (1 copy) | |
| Other Names of Target: | ABC-D 1; ABC 42; ALD; ALDP; AMN; Adrenoleukodystrophy protein; ATP-Binding cassette, Subfamily D (ALD) member 1 |
Target information
Plays a role in the transport of free very-long-chain fatty acids (VLCFAs) as well as their CoA-esters across the peroxisomal membrane by acting as an ATP-specific binding subunit releasing ADP after ATP hydrolysis (By similarity). Thus, plays a role in regulation of VLCFAs and energy metabolism namely, in the degradation and biosynthesis of fatty acids by beta-oxidation, mitochondrial function and microsomal fatty acid elongation (PubMed:25255441, PubMed:9418970, PubMed:9126326, PubMed:9256488, PubMed:18854420, PubMed:23123468, PubMed:26108493, PubMed:23604518, PubMed:25583114). Involved in several processes; namely, controls the active myelination phase by negatively regulating the microsomal fatty acid elongation activity and may also play a role in axon and myelin maintenance (PubMed:11875044, PubMed:26108493, PubMed:15489218). Controls also the cellular response to oxidative stress by regulating mitochondrial function like, mitochondrial oxidative phosphorylation and depolarization (PubMed:25583114, PubMed:23604518, PubMed:18344354, PubMed:22521832). And finally controls the inflammatory response by positively regulating peroxisomal beta-oxidation of VLCFAs (PubMed:18723473).
References
Erpantech Laboratory