Human Myelin Basic Protein ELISA kit
Specifications
| Product Cat#: | EK-07-0231 |
| Product name: | Human Myelin Basic Protein ELISA kit |
| Target Name: | MBP |
| Species Reactivity: | Human |
| Product Size: | 48/96 Tests |
| Sensitivity: | 0.06 µg/mL |
| Assay range: | 0.5-10 ng/mL |
| Assay Time: | 90 minutes |
| Platform: | Colorimetric Microplate Reader |
| Conjugate: | HRP |
| ELISA Type: | Competitive ELISA |
| Detection Method: | Colorimetric |
| Storage temperature: | Store at 2-8°C |
| Stability: | Stable within the expiration date under suggested storage conditions |
| Shipping condition: | Wet ice |
| Kit Contents: | Microtiter plate ( 1x ), Enzyme conjugate ( 1 vial ), Standard samples ( 6 vials ), |
| Substrates ( A & B, 2 vials ), Stop solution ( 1 vial ), Wash Solution ( 100x, 1 vial ), | |
| Balance solution ( 1 vial ), Instruction ( 1 copy ) | |
| Other Names of Target: | Acylation-stimulating Protein Cleavage Product; AHUS5; ARMD9; ASP; C3 and PZP-like Alpha-2-macroglobulin Domain-containing Protein 1 Antibody C3 Antibody C3a Anaphylatoxin; CO3_HUMAN; Complement C3 Alpha Chain; Complement C3; Complement C3 Beta Chain; Complement C3 precursor; Complement C3b Alpha Chain; Complement C3c Alpha'Chain Fragment 2; Complement C3c Fragment; Complement C3d fragment; Complement C3f fragment; Complement C3g Fragment; Complement Component 3; Complement Component 3 Precursor; Complement Component C3; Complement Factor 3; CPAMD1; Plp |
Target information
The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. Induces T-cell proliferation.
Provider
Erpantech Laboratory
