Human Indoleamine 2,3 Dioxygenase ELISA kit
Specifications
| Product Cat#: | EK-07-0182 |
| Product name: | Human Indoleamine 2,3 Dioxygenase ELISA kit |
| Target Name: | IDO |
| Species Reactivity: | Human |
| Product Size: | 48/96 Tests |
| Sensitivity: | 1.57 ng/mL |
| Assay range: | 10-250 ng/mL |
| Assay Time: | 90 minutes |
| Platform: | Colorimetric Microplate Reader |
| Conjugate: | HRP |
| ELISA Type: | Competitive ELISA |
| Detection Method: | Colorimetric |
| Storage temperature: | Store at 2-8°C |
| Stability: | Stable within the expiration date under suggested storage conditions |
| Shipping condition: | Wet ice |
| Kit Contents: | Microtiter plate ( 1x ), Enzyme conjugate ( 1 vial ), Standard samples ( 6 vials ), |
| Substrates ( A & B, 2 vials ), Stop solution ( 1 vial ), Wash Solution ( 100x, 1 vial ), | |
| Balance solution ( 1 vial ), Instruction ( 1 copy ) | |
| Other Names of Target: | Indoleamine 2, 3-dioxygenase ; 3-dioxygenase; I23O1_HUMAN; IDO 1; INDO; Indole 2 3 Dioxygenase;Indoleamine 2 3 Dioxygenase 1; Indoleamine 2 3 Dioxygenase; Indoleamine Pyrrole 2 3 Dioxygenase; Indoleamine-pyrrole 2 |
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Target information
Catalyzes the first and rate limiting step of the catabolism of the essential amino acid tryptophan along the kynurenine pathway. Involved in the peripheral immune tolerance, contributing to maintain homeostasis by preventing autoimmunity or immunopathology that would result from uncontrolled and overreacting immune responses Tryptophan shortage inhibits T lymphocytes division and accumulation of tryptophan catabolites induces T-cell apoptosis and differentiation of regulatory T-cells. Acts as a suppressor of anti-tumor immunity.Limits the growth of intracellular pathogens by depriving tryptophan. Protects the fetus from maternal immune rejection.
Provider
Erpantech Laboratory
