Human Cx3CL1/Fractalkine ELISA Kit
Specifications
Product Cat#:
EK-07-0088
Product name:
Human Cx3CL1/Fractalkine ELISA Kit
Target Name:
Cx3CL1
Species Reactivity:
Human
Product Size:
48/96 Tests
Sensitivity:
0.05 ng/mL
Assay range:
0.5-10 ng/mL
Assay Time:
90 minutes
Platform:
Colorimetric Microplate Reader
Conjugate:
HRP
ELISA Type:
Sandwich ELISA
Detection Method:
Colorimetric
Storage temperature:
Store at 2-8°C
Stability:
Stable within the expiration date under suggested storage conditions
Shipping condition:
Wet ice
Kit Contents:
Microtiter plate (1x), Enzyme conjugate (1 vial), Standard samples (6 vials),
Substrates (A & B, 2 vials), Stop solution (1 vial), Wash Solution (100x, 1 vial),
Balance solution (1 vial), Instruction (1 copy)
Other Names of Target:
C3Xkine; Chemokine C X3 C motif ligand 1; CX3C membrane anchored chemokine; CXC3; CXC3C; FKN; Fractalkine; Neurotactin; NTN; NTT; SCYD 1; SCYD1; Small inducible cytokine D1; Small inducible cytokine subfamily D (Cys X3 Cys) member 1; Small inducible cytokine subfamily D member 1.
Target information
Acts as a ligand for both CX3CR1 and integrins. Binds to CX3CR1. Binds to integrins ITGAV:ITGB3 and ITGA4:ITGB1. Can activate integrins in both a CX3CR1-dependent and CX3CR1-independent manner. In the presence of CX3CR1, activates integrins by binding to the classical ligand-binding site (site 1) in integrins. In the absence of CX3CR1, binds to a second site (site 2) in integrins which is distinct from site 1 and enhances the binding of other integrin ligands to site 1. The soluble form is chemotactic for T-cells and monocytes and not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium .
Provider
Erpantech Laboratory
