Human Caspase 3 ELISA Kit
Specifications
| Product Cat#: | EK-07-0095 |
| Product name: | Human Caspase 3 ELISA Kit |
| Target Name: | CASP-3 |
| Species Reactivity: | Human |
| Product Size: | 48/96 Tests |
| Sensitivity: | 0.07 ng/mL |
| Assay range: | 0.5-10 ng/mL |
| Assay Time: | 90 minutes |
| Platform: | Colorimetric Microplate Reader |
| Conjugate: | HRP |
| ELISA Type: | Competitive ELISA |
| Detection Method: | Colorimetric |
| Storage temperature: | Store at 2-8°C |
| Stability: | Stable within the expiration date under suggested storage conditions |
| Shipping condition: | Wet ice |
| Kit Contents: | Microtiter plate (1x), Enzyme conjugate (1 vial), Standard samples (6 vials), |
| Substrates (A & B, 2 vials), Stop solution (1 vial), Wash Solution (100x, 1 vial), | |
| Balance solution (1 vial), Instruction (1 copy) | |
| Other Names of Target: | Caspase-3 subunit p17; APOPAIN; Caspase 3 apoptosis related cysteine protease; CPP32; CPP32B; Cysteine protease CPP32; Human cysteine protease CPP32 isoform alpha mRNA complete cds; PARP cleavage protease; SCA1; SREBP cleavage activity 1; Yama; CASP-3; Apopain; Protein Yama; SREBP cleavage activity 1; SCA-1. |
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Target information
Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a ‘216-Asp-|-Gly-217’ bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage.
Provider
Erpantech Laboratory
