FITC-labeled Rat Anti-Mouse Integrin β3 chain (GPIIIa, CD61)Monoclonal Antibody
Specifications
| Product Cat#: | M031-1 |
| Product type: | Primary antibody |
| Antigen: | Integrin β3 chain (GPIIIa, CD61) |
| Immunogen: | Recombinant protein |
| Species immunized: | Rat |
| Isotype: | IgG2b |
| Applications: | Immunohistochemistry; Flow Cytometry |
| Reactivity: | Mouse |
| Clonality (clone number): | Monoclonal, Luc.H11 |
| Form: | Liquid |
| Buffer: | FITC-labeled immunoglobulin in 20 mM Tris buffer with 137 mM NaCl, 0.5%BSA and 0.09% (w/v) sodium azide |
| Concentration: | - mg/mL |
| Purity: | Protein G affinity purified. |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Integrin beta-3; Platelet membrane glycoprotein IIIa; Itgb3 |
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Target information
The Luc.H11 antibody reacts with murine and human integrin beta3 chain (GPIIIa, CD61). This glycoprotein non-covalently associates with the alphaIIb chain (CD41) to form the activation dependent platelet receptor for fibrinogen, von Willebrand factor, fibronectin, and vitronectin. Alternatively, it associates with the alphav chain (CD51) to form the integrin alphav beta3, that mediates adhesion to vitronectin, vWf, fibrinogen, and thrombospondin on platelets, monocytes, activated lymphocytes, and granulocytes.
Provider
Erpantech Laboratory
