Anti-ZNF93 antibody
Specifications
| Product Cat#: | AB-06-4727 |
| Product type: | Primary antibody |
| Antigen: | ZNF93 |
| Immunogen: | KLH conjugated synthetic peptide derived from human ZBT24/ZNF45 521-620/620 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2000) |
| Reactivity: | Human |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 10mM Tris-HCl buffer (pH7.4), 1% BSA, 50% glycerol, 0.03% Proclin300. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | FLJ12488 |
| HPF34 | |
| HTF34 | |
| TF34 | |
| Zinc finger protein 505 | |
| Zinc finger protein 93 (HTF34) | |
| Zinc finger protein 93 | |
| Zinc finger protein HTF34 | |
| ZNF505 | |
| ZNF93 |
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Target information
Transcription factor specifically required to repress long interspersed nuclear element 1 (L1) retrotransposons: recognizes and binds L1 sequences and repress their expression by recruiting a repressive complex containing TRIM28/KAP1 (PubMed:25274305). Not able to repress expression of all subtypes of L1 elements. Binds to the 5′ end of L1PA4, L1PA5 and L1PA6 subtypes, and some L1PA3 subtypes. Does not bind to L1PA7 or older subtypes nor at the most recently evolved L1PA2 and L1Hs. 50% of L1PA3 elements have lost the ZNF93-binding site, explaining why ZNF93 is not able to repress their expression (PubMed:25274305).
Provider
Erpantech Laboratory