Anti-ZBTB48 antibody
Specifications
| Product Cat#: | AB-06-4687 |
| Product type: | Primary antibody |
| Antigen: | ZBTB48 |
| Immunogen: | Peptide |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:1000); Immunohistochemistry (1:50-1:200); Flow Cytometry (1:50-1:200); Immunocytochemistry (1:50-1:200) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 0.5% BSA, 50% glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Peptide affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | 0610011D15Rik antibody |
| AI327031 antibody | |
| GLI Kruppel family member HKR3 antibody | |
| HKR3 antibody | |
| Krueppel related zinc finger protein 3 antibody | |
| Krueppel-related zinc finger protein 3 antibody | |
| OTTMUSP00000031803 antibody | |
| pp9964 antibody | |
| Protein HKR3 antibody | |
| RP23-445E20.3 antibody | |
| ZBT48_HUMAN antibody | |
| ZBTB 48 antibody | |
| Zbtb48 antibody | |
| Zinc finger and BTB domain containing 48 antibody | |
| Zinc finger and BTB domain containing protein 48 antibody | |
| Zinc finger and BTB domain-containing protein 48 antibody | |
| Zinc finger protein 855 antibody | |
| ZNF855 antibody |
Target information
Telomere-binding protein that acts as a regulator of telomere length (PubMed:28500257, PubMed:28082411). Directly binds the telomeric double-stranded 5′-TTAGGG-3′ repeat (PubMed:28500257, PubMed:28082411). Preferentially binds to telomeres that have a low concentration of shelterin complex and acts as a regulator of telomere length by initiating telomere trimming, a process that prevents the accumulation of aberrantly long telomeres (PubMed:28082411). Also acts as a transcription regulator that binds to promoter regions (PubMed:7969177, PubMed:24382891, PubMed:28500257). Regulates expression of a small subset of genes, including MTFP1 (PubMed:28500257). Regulates expression the J and/or S elements in MHC II promoter (PubMed:7969177). Acts as a negative regulator of cell proliferation by specifically activating expression of ARF, a tumor suppressor isoform of CDKN2A (PubMed:24382891).
Provider
Erpantech Laboratory
