Anti-ZAK (Ab-165) antibody
Specifications
| Product Cat#: | AB-07-2244 |
| Product type: | Primary antibody |
| Antigen: | ZAK (Ab-165) |
| Immunogen: | The antiserum was produced against synthesized non-phosphopeptide derived from human ZAK around the phosphorylation site of serine 165 (H-M-SP -L-V). |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2500); ELISA (1:35000) |
| Reactivity: | Human, Mouse |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Antigen affinity chromatography |
| Storage: | Aliquot and freeze at -20°C. Avoid multiple freeze/thaw cycles. |
| Alternative names: | AZK; EC 2.7.11.25; Mixed lineage kinase-related kinase; MLTK; MRK-beta; Sterile alpha motif and leucine zipper containing kinase AZK |
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Target information
Positive regulator of gsk3/gskA activity required for cell pattern formation and a downstream effector of carC. The kinases, gsk3/gskA, zakA and zak2, form part of a signaling pathway that responds to extracellular cyclic AMP. The pathway has a role in transcriptional regulation; required to direct prespore/spore fates during development. Zak2 negatively regulates prestalk differentiation by regulating expression of ecmA. Phosphorylates Y-214 of gsk3/gskA, in vitro.
Provider
Erpantech Laboratory
