Anti-YB1 antibody
Specifications
| Product cat: | AB-06-4677 |
| Product type: | Primary antibody |
| Antigen: | YB1 |
| Immunogen: | recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:900-1:2400); Immunohistochemistry (1:90-1:260); Immunocytochemistry (1:100-1:250); Flow Cytometry (1:70-1:260); Immunoprecipitation; Immunofluorescence |
| Reactivity: | Mouse, Rat and Human |
| Clonality (clone number): | Monoclonal (ST0432) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | BP 8 antibody |
| CBF-A antibody | |
| CCAAT binding transcription factor I subunit A antibody | |
| CCAAT-binding transcription factor I subunit A antibody | |
| CSDA2 antibody | |
| CSDB antibody | |
| DBPB antibody | |
| DNA binding protein B antibody | |
| DNA-binding protein B antibody | |
| EFI-A antibody | |
| Enhancer factor I subunit A antibody | |
| MDR NF1 antibody | |
| MGC104858 antibody | |
| MGC110976 antibody | |
| MGC117250 antibody | |
| NSEP 1 antibody | |
| NSEP1 antibody | |
| Nuclease sensitive element binding protein 1 antibody | |
| Nuclease-sensitive element-binding protein 1 antibody | |
| p50 antibody | |
| Q15905 antibody | |
| Y-box binding protein 1 antibody | |
| Y-box transcription factor antibody | |
| Y-box-binding protein 1 antibody | |
| YB 1 antibody | |
| YB-1 antibody | |
| YBOX1_HUMAN antibody | |
| YBX 1 antibody | |
| ybx1 antibody |
Target information
Mediates pre-mRNA alternative splicing regulation. Binds to splice sites in pre-mRNA and regulates splice site selection. Binds and stabilizes cytoplasmic mRNA. Contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors (By similarity). Regulates the transcription of numerous genes. Its transcriptional activity on the multidrug resistance gene MDR1 is enhanced in presence of the APEX1 acetylated form at ‘Lys-6’ and ‘Lys-7’. Binds to promoters that contain a Y-box (5′-CTGATTGGCCAA-3′), such as MDR1 and HLA class II genes. Promotes separation of DNA strands that contain mismatches or are modified by cisplatin. Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro). May play a role in DNA repair. Component of the CRD-mediated complex that promotes MYC mRNA stability. Binds preferentially to the 5′-[CU]CUGCG-3′ motif in vitro.
The secreted form acts as an extracellular mitogen and stimulates cell migration and proliferation.
Provider
Erpantech Laboratory