Anti-WWOX (Phospho-Tyr33) antibody
Specifications
| Product Cat#: | AB-07-2235 |
| Product type: | Primary antibody |
| Antigen: | WWOX (Phospho-Tyr33) |
| Immunogen: | The antiserum was produced against synthesized phosphopeptide derived from human WWOX around the phosphorylation site of tyrosine 33 (W-V-YP -Y-A). |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2500); Immunohistochemistry (1:50-1:100); ELISA (1:7500) |
| Reactivity: | Human, Mouse |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Antigen affinity chromatography |
| Storage: | Aliquot and freeze at -20°C. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Aberrant WW domain-containing oxidoreductase; EC 1.1.1.-; FOR; WOX1; WW domain-containing oxidoreductase |
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Target information
Putative oxidoreductase. Acts as a tumor suppressor and plays a role in apoptosis. Required for normal bone development (By similarity). May function synergistically with p53/TP53 to control genotoxic stress-induced cell death. Plays a role in TGFB1 signaling and TGFB1-mediated cell death. May also play a role in tumor necrosis factor (TNF)-mediated cell death. Inhibits Wnt signaling, probably by sequestering DVL2 in the cytoplasm.
Provider
Erpantech Laboratory
