Anti-WWOX antibody
Specifications
| Product type: | Primary antibody |
| Antigen: | WWOX |
| Immunogen: | KLH conjugated synthetic peptide derived from human WWOX 5-100/414 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot(1:450-1:2000); Flow Cytometry(1ug/test); Immunohistochemistry-Paraffin(1:450-1:800) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 50% glycerol, 0.03% Proclin |
| Concentration: | 1mg/ml |
| Purity: | Protein A affinity purified. |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | D16S432E |
| FOR | |
| FOR II protein | |
| FRA16D | |
| Fragile 16D oxido reductase | |
| Fragile site FRA16D oxidoreductase | |
| HHCMA 56 | |
| HHCMA56 | |
| PRO0128 | |
| Putative oxidoreductase | |
| WOX 1 | |
| WOX1 | |
| WW domain containing oxidoreductase | |
| WW domain-containing protein WWOX | |
| WWOX2 | |
| WWOX4 | |
| WWOX8 |
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Target information
Putative oxidoreductase. Acts as a tumor suppressor and plays a role in apoptosis. Required for normal bone development (By similarity). May function synergistically with p53/TP53 to control genotoxic stress-induced cell death. Plays a role in TGFB1 signaling and TGFB1-mediated cell death. May also play a role in tumor necrosis factor (TNF)-mediated cell death. Inhibits Wnt signaling, probably by sequestering DVL2 in the cytoplasm.
Provider
Erpantech Laboratory
