Anti-Wilms Tumor Protein antibody
Specifications
| Product type: | Primary antibody |
| Antigen: | Wilms Tumor Protein |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:900-1:2000); Immunohistochemistry(1:40-1:200); Immunocytochemistry (1:40-1:200); Flow Cytometry (1:40-1:100); Immunofluorescence |
| Reactivity: | Human, Mouse |
| Clonality (clone number): | Monoclonal (SC06-41) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | WIT 2 antibody |
| WT 1 antibody | |
| AWT1 antibody | |
| FWT1 antibody | |
| GUD antibody | |
| NPHS4 antibody | |
| WAGR antibody | |
| Wilms tumor 1 antibody | |
| Wilms Tumor antibody | |
| Wilms tumor protein antibody | |
| Wilms' tumor gene antibody | |
| Wilms' tumor protein antibody | |
| WIT2 antibody | |
| WT antibody | |
| WT1 antibody | |
| WT1_HUMAN antibody | |
| WT33 antibody |
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Target information
Transcription factor that plays an important role in cellular development and cell survival . Recognizes and binds to the DNA sequence 5′-GCG(T/G)GGGCG-3′ . Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors . Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing . Isoform 1 has lower affinity for DNA, and can bind RNA .
Provider
Erpantech Laboratory
