Anti-VEGF Recombinant Rabbit Monoclonal antibody
Specifications
| Product Cat#: | AB-06-4588 |
| Product type: | Primary antibody |
| Antigen: | VEGF |
| Immunogen: | Synthetic peptide within Human VEGF aa 183-232 / 232. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2000); Flow Cytometry (1:50-1:100); Immunocytochemistry/Immunofluorescence (1:50-1:200); Immunoprecipitation; Immunohistochemistry-Paraffin (1:50-200) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Monoclonal (SP07-01) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 0.05% BSA; 40% glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Folliculostellate cell-derived growth factor antibody |
| Glioma-derived endothelial cell mitogen antibody | |
| MGC70609 antibody | |
| MVCD1 antibody | |
| Vascular endothelial growth factor A antibody | |
| Vascular endothelial growth factor A121 antibody | |
| Vascular endothelial growth factor A165 antibAody | |
| Vascular endothelial growth factor antibody | |
| Vascular permeability factor antibody | |
| VEGF A antibody | |
| Vegf antibody | |
| VEGF-A antibody | |
| VEGF120 antibody | |
| Vegfa antibody | |
| VEGFA_HUMAN antibody | |
| VPF antibody |
Target information
Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development (By similarity).
Provider
Erpantech Laboratory
