Anti-VDAC1 antibody
Specifications
| Product Cat#: | AB-06-4584 |
| Product type: | Primary antibody |
| Antigen: | VDAC1 |
| Immunogen: | Peptide |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot(1:450); Immunocytochemistry(1:190); Immunohistochemistry(1:190) |
| Reactivity: | Human, Zebrafish |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH7.4), 1% BSA; 40% glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Immunogen affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | HVDAC1 antibody |
| Outer mitochondrial membrane protein porin 1 antibody | |
| Plasmalemmal porin antibody | |
| Porin 31HL antibody | |
| Porin 31HM antibody |
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Target information
Forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules; in the plasma membrane it is involved in cell volume regulation and apoptosis. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective . May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis.
Provider
Erpantech Laboratory
