Anti-USP11 antibody
Specifications
| Product Cat#: | AB-06-4552 |
| Product type: | Primary antibody |
| Antigen: | USP11 |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:400-1:1000); Flow Cytometry (1:40-1:100); Immunocytochemistry (1:40-1:200); Immunoprecipitation; Immunofluorescence |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Monoclonal (JM33-62) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH 7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Deubiquitinating enzyme 11 antibody |
| Ubiquitin carboxyl-terminal hydrolase 11 antibody | |
| Ubiquitin carboxyl-terminal hydrolase X linked antibody | |
| Ubiquitin specific peptidase 11 antibody | |
| Ubiquitin specific protease 11 antibody | |
| Ubiquitin thiolesterase 11 antibody | |
| Ubiquitin-specific-processing protease 11 antibody | |
| UBP11_HUMAN antibody | |
| UHX1 antibody | |
| USP11 antibody |
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Target information
Protease that can remove conjugated ubiquitin from target proteins and polyubiquitin chains. Inhibits the degradation of target proteins by the proteasome. Cleaves preferentially ‘Lys-6’ and ‘Lys-63’-linked ubiquitin chains. Has lower activity with ‘Lys-11’ and ‘Lys-33’-linked ubiquitin chains, and extremely low activity with ‘Lys-27’, ‘Lys-29’ and ‘Lys-48’-linked ubiquitin chains (in vitro) . Plays a role in the regulation of pathways leading to NF-kappa-B activation. Plays a role in the regulation of DNA repair after double-stranded DNA breaks. Acts as a chromatin regulator via its association with the Polycomb group (PcG) multiprotein PRC1-like complex; may act by deubiquitinating components of the PRC1-like complex.
Provider
Erpantech Laboratory
