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Anti-UCP-1 antibody

SKU Product Brand Unit Availability Price Quantity  
AB-06-4528
Anti-UCP-1 antibody
Erpan Tech In stock

Specifications        

Product Cat#: AB-06-4528
Product type: Primary antibody
Antigen: UCP-1
Immunogen: KLH conjugated synthetic peptide derived from human UCP-1 101-200/307
Species immunized: Rabbit
Isotype: IgG
Applications: Western Blot (1:400-1:2000); Flow Cytometry (2μg /test)
Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep
Clonality (clone number): Polyclonal
Form: Liquid
Buffer: 10 mM Tris-HCl buffer (pH 7.4), 1% BSA, 50% glycerol, 0.03% Proclin300.
Concentration: 1 mg/ml
Purity: Protein A affinity purified
Storage: Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles.
Alternative names: Uncoupling Protein-1
UCP1
UCP 1
Mitochondrial brown fat uncoupling protein 1
Mitochondrial brown fat uncoupling protein
SLC25A7
Thermogenin
UCP 1
UCP
Uncoupling protein 1
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Target information

Mitochondrial protein responsible for thermogenic respiration, a specialized capacity of brown adipose tissue and beige fat that participates to non-shivering adaptive thermogenesis to temperature and diet variations and more generally to the regulation of energy balance . Functions as a long-chain fatty acid/LCFA and proton symporter, simultaneously transporting one LCFA and one proton through the inner mitochondrial membrane. However, LCFAs remaining associated with the transporter via their hydrophobic tails, it results in an apparent transport of protons activated by LCFAs. Thereby, dissipates the mitochondrial proton gradient and converts the energy of substrate oxydation into heat instead of ATP. Regulates the production of reactive oxygen species/ROS by mitochondria.

Provider

Erpantech Laboratory

download

MSDS-AB-06-4528.pdf (173 downloads)