Anti-UCP-1 antibody
Specifications
| Product Cat#: | AB-06-4528 |
| Product type: | Primary antibody |
| Antigen: | UCP-1 |
| Immunogen: | KLH conjugated synthetic peptide derived from human UCP-1 101-200/307 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:400-1:2000); Flow Cytometry (2μg /test) |
| Reactivity: | Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 10 mM Tris-HCl buffer (pH 7.4), 1% BSA, 50% glycerol, 0.03% Proclin300. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Uncoupling Protein-1 |
| UCP1 | |
| UCP 1 | |
| Mitochondrial brown fat uncoupling protein 1 | |
| Mitochondrial brown fat uncoupling protein | |
| SLC25A7 | |
| Thermogenin | |
| UCP 1 | |
| UCP | |
| Uncoupling protein 1 |
Target information
Mitochondrial protein responsible for thermogenic respiration, a specialized capacity of brown adipose tissue and beige fat that participates to non-shivering adaptive thermogenesis to temperature and diet variations and more generally to the regulation of energy balance . Functions as a long-chain fatty acid/LCFA and proton symporter, simultaneously transporting one LCFA and one proton through the inner mitochondrial membrane. However, LCFAs remaining associated with the transporter via their hydrophobic tails, it results in an apparent transport of protons activated by LCFAs. Thereby, dissipates the mitochondrial proton gradient and converts the energy of substrate oxydation into heat instead of ATP. Regulates the production of reactive oxygen species/ROS by mitochondria.
Provider
Erpantech Laboratory
