Anti-Ubiquitin-like modifier-activating enzyme 1 antibody
Specifications
| Product Cat#: | AB-06-4524 |
| Product type: | Primary antibody |
| Antigen: | Ubiquitin-like modifier-activating enzyme 1 |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:800-1:2000); Immunohistochemistry (1:80-1:500); Flow Cytometry (1:40-1:100); Immunocytochemistry (1:40-1:200); Immunofluorescence |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Monoclonal (SD08-62) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH 7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | A1S9 antibody |
| A1S9 protein antibody | |
| A1S9T and BN75 temperature sensitivity complementing antibody | |
| A1S9T antibody | |
| A1ST antibody | |
| AMCX1 antibody | |
| CFAP124 antibody | |
| CTD-2522E6.1 antibody | |
| GXP 1 antibody | |
| GXP1 antibody | |
| MGC4781 antibody | |
| POC20 antibody | |
| POC20 centriolar protein homolog antibody | |
| Protein A1S9 antibody | |
| SMAX2 antibody | |
| Uba1 antibody | |
| UBA1, ubiquitin-activating enzyme E1 homolog A antibody | |
| UBA1_HUMAN antibody | |
| UBA1A antibody | |
| UBE 1 antibody | |
| UBE 1X antibody | |
| UBE1 antibody | |
| UBE1X antibody | |
| Ubiquitin activating enzyme E1 antibody | |
| Ubiquitin-activating enzyme E1 antibody | |
| Ubiquitin-like modifier-activating enzyme 1 antibody |
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Target information
Catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation through the ubiquitin-proteasome system . Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP . Essential for the formation of radiation-induced foci, timely DNA repair and for response to replication stress. Promotes the recruitment of TP53BP1 and BRCA1 at DNA damage sites.
Provider
Erpantech Laboratory