Anti-Tuberin antibody
Specifications
| Product Cat#: | AB-06-4489 |
| Product type: | Primary antibody |
| Antigen: | Tuberin |
| Immunogen: | Recombinant protein |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:800-1:2000); Immunohistochemistry (1:40-1:200); Flow Cytometry (1:40-1:100) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Monoclonal (SC05-59) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH 7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | FLJ43106 antibody |
| LAM antibody | |
| OTTHUMP00000158940 antibody | |
| OTTHUMP00000198394 antibody | |
| OTTHUMP00000198395 antibody | |
| PPP1R160 antibody | |
| Protein phosphatase 1, regulatory subunit 160 antibody | |
| Tsc2 antibody | |
| TSC2_HUMAN antibody | |
| TSC4 antibody | |
| TSC4 gene, formerly antibody | |
| TSC4, formerly antibody | |
| Tuberin antibody | |
| Tuberous sclerosis 2 antibody | |
| Tuberous sclerosis 2 protein antibody | |
| Tuberous sclerosis 2 protein homolog antibody |
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Target information
In complex with TSC1, this tumor suppressor inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, a direct activator of the protein kinase activity of mTORC1. May also play a role in microtubule-mediated protein transport (By similarity). Also stimulates the intrinsic GTPase activity of the Ras-related proteins RAP1A and RAB5 (By similarity).
Provider
Erpantech Laboratory