Anti-TTR antibody
Specifications
| Product Cat#: | AB-06-4486 |
| Product type: | Primary antibody |
| Antigen: | TTR |
| Immunogen: | Recombinant protein |
| Species immunized: | Mouse |
| Isotype: | IgG1 |
| Applications: | Western Blot (1:400-1:2000); Immunohistochemistry (1:40-1:200); Flow Cytometry (1:40-1:100); Immunocytochemistry (1:40-1:200) |
| Reactivity: | Human |
| Clonality (clone number): | Monoclonal (C5-E10) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH 7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Amyloid polyneuropathy antibody |
| Amyloidosis I antibody | |
| ATTR antibody | |
| Carpal tunnel syndrome 1 antibody | |
| CTS antibody | |
| CTS1 antibody | |
| Dysprealbuminemic euthyroidal hyperthyroxinemia antibody | |
| Dystransthyretinemic hyperthyroxinemia antibody | |
| Epididymis luminal protein 111 antibody | |
| HEL111 antibody | |
| HsT2651 antibody | |
| PALB antibody | |
| Prealbumin amyloidosis type I antibody | |
| Prealbumin antibody | |
| Prealbumin Thyroxine-binding antibody | |
| Senile systemic amyloidosis antibody | |
| TBPA antibody | |
| Thyroxine binding prealbumin antibody | |
| Transthyretin antibody | |
| TTHY_HUMAN antibody | |
| TTR antibody | |
| TTR protein antibody |
Target information
Prealbumin, also designated transthyretin, is a major thyroid-hormone binding protein involved in transporting thyroxine from the bloodstream to the brain. Prealbumin is located in the cytoplasm and in the vesicles of developing rat brain cells, and is thought to be transported there from the cerebrospinal fluid via endocytosis. Sequence variants of this protein have been identified in amyloid fibrils from patients with familial amyloidotic polyneuropathy (FAP), the most common form of hereditary systemic amyloidosis. Although the biologically active form of Prealbumin is a tetramer, the amyloidogenic intermed-iate is thought to be a monomeric species. Prealbumin also binds to the retinol carrier protein RBP (retinol-binding protein). The gene encoding Prealbumin maps to human chromosome 18q12.1.
Provider
Erpantech Laboratory