Anti-TP53INP2 antibody
Specifications
| Product Cat#: | AB-07-3907 |
| Product type: | Primary antibody |
| Antigen: | TP53INP2 |
| Immunogen: | A synthetic peptide derived from human TP53INP2. The exact amino-acid sequence is proprietary. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Immunohistochemistry (1:50-1:100); Immunofluorescence (1:100-1:500); ELISA (1:10000) |
| Reactivity: | Human, Mouse and Rat |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Antigen affinity chromatography |
| Storage: | Aliquot and freeze at -20°C. Avoid multiple freeze/thaw cycles. |
| Alternative names: | P53-inducible protein U; PIG-U; PINH; T53I2; tumor protein p53 inducible nuclear protein 2; tumor protein p53-inducible nuclear protein 2 |
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Target information
Dual regulator of transcription and autophagy. Positively regulates autophagy and is required for autophagosome formation and processing. May act as a scaffold protein that recruits MAP1LC3A, GABARAP and GABARAPL2 and brings them to the autophagosome membrane by interacting with VMP1 where, in cooperation with the BECN1-PI3-kinase class III complex, they trigger autophagosome development. Acts as a transcriptional activator of THRA.
Provider
Erpantech Laboratory
