Anti-TOP2A antibody
Specifications
| Product Cat#: | AB-07-1376 |
| Product type: | Primary antibody |
| Antigen: | TOP2A |
| Immunogen: | A synthetic peptide derived from human TOP2A. The exact amino-acid sequence is proprietary. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2500); Immunohistochemistry (1:50-1:100); Immunofluorescence (1:100-1:500); ELISA (1:20000) |
| Reactivity: | Human |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | PBS (without Mg2+ and Ca2+ ), pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol |
| Concentration: | 1 mg/ml |
| Purity: | Antigen affinity chromatography |
| Storage: | Aliquot and freeze at -20°C. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Alpha isozyme; DNA topoisomerase II; DNA topoisomerase II-alpha; P11388-1; TOP-2; TOP2; TOP2A; TP2A |
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Target information
Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation (By similarity).
Provider
Erpantech Laboratory
