Anti-TNFR1 antibody
Specifications
| Product Cat#: | AB-06-4396 |
| Product type: | Primary antibody |
| Antigen: | TNFR1 |
| Immunogen: | Synthetic peptide (KLH-coupled) corresponding to the aa 210-250 of human TESPA1. |
| Species immunized: | Mouse |
| Isotype: | IgG |
| Applications: | Western Blot (1:50-1:1000); Immunohistochemistry (1:100-1:500); Immunoprecipitation [1-2 μg per 50-500 μg of total protein(1 ml of cell lysate)]; Immunofluorescence (1:100-1:500) |
| Reactivity: | Human, Mouse, Rat |
| Clonality (clone number): | Monoclonal (2G2) |
| Form: | Liquid |
| Buffer: | Tris-HCl buffer (pH 7.4), 1% BSA, 40% glycerol, 0.05% NaN3. |
| Concentration: | 1 mg/ml |
| Purity: | Immunogen affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | CD120a antibody |
| FPF antibody | |
| MGC19588 antibody | |
| P55 antibody | |
| P55-R antibody | |
| P60 antibody | |
| TBP1 antibody | |
| TBPI antibody | |
| TNF R antibody | |
| TNF R55 antibody | |
| TNF-R1 antibody | |
| TNF-RI antibody | |
| TNFAR antibody | |
| TNFR-I antibody | |
| TNFR1 antibody | |
| TNFR55 antibody | |
| TNFR60 antibody | |
| TNFRI antibody | |
| TNFRSF1a antibody | |
| TNR1A_HUMAN antibody | |
| Tumor necrosis factor receptor 1 antibody | |
| Tumor necrosis factor receptor superfamily, member 1A antibody | |
| Tumor necrosis factor receptor type 1 antibody | |
| Tumor necrosis factor receptor type I antibody | |
| Tumor necrosis factor-binding protein 1 antibody |
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Target information
Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.
Provider
Erpantech Laboratory