Anti-TNF12 antibody
Specifications
| Product Cat#: | AB-07-2189 |
| Product type: | Primary antibody |
| Antigen: | TNF12 |
| Immunogen: | The antiserum was produced against synthesized peptide derived from internal of human TNF12. |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:500-1:2500); Immunohistochemistry (1:50-1:100); Immunofluorescence (1:100-1:500); ELISA (1:15000) |
| Reactivity: | Human, Mouse |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Concentration: | 1 mg/ml |
| Purity: | Antigen affinity chromatography |
| Storage: | Aliquot and freeze at -20°C. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Tumor necrosis factor ligand superfamily member 12, TNF-related weak inducer of apoptosis, TWEAK, APO3 ligand, Tumor necrosis factor ligand superfamily member 12, Membrane form, Tumor necrosis factor ligand superfamily member 12, secreted form, TNFSF12, APO3L, DR3LG, UNQ181/PRO207 |
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Target information
Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Promotes IL8 secretion.
Provider
Erpantech Laboratory
