Anti-TMEM49 antibody
Specifications
| Product Cat#: | AB-06-4384 |
| Product type: | Primary antibody |
| Antigen: | TMEM49 |
| Immunogen: | KLH conjugated synthetic peptide derived from human TMEM49 361-406/406 |
| Species immunized: | Rabbit |
| Isotype: | IgG |
| Applications: | Western Blot (1:400-1:2000); Immunohistochemistry-Paraffin (1:500-1:800) |
| Reactivity: | Human, Mouse, Rat, Pig, Horse, Rabbit |
| Clonality (clone number): | Polyclonal |
| Form: | Liquid |
| Buffer: | 10 mM Tris-HCl buffer (pH 7.4), 1% BSA, 50% glycerol, 0.03% Proclin300 |
| Concentration: | 1 mg/ml |
| Purity: | Protein A affinity purified |
| Storage: | Aliquot and freeze at -20℃. Avoid multiple freeze/thaw cycles. |
| Alternative names: | Vacuole membrane protein 1 |
| DKFZP566I133 | |
| TDC1 | |
| TMEM49 | |
| Transmembrane protein 49 | |
| Vmp1 |
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Target information
Stress-induced protein that, when overexpressed, promotes formation of intracellular vacuoles followed by cell death. May be involved in the cytoplasmic vacuolization of acinar cells during the early stage of acute pancreatitis. Plays a role in the initial stages of the autophagic process through its interaction with BECN1 (By similarity). Involved in cell-cell adhesion. Plays an essential role in formation of cell junctions. Required for autophagosome formation.
Provider
Erpantech Laboratory